Whether it is to enhance the hydration and lubrication of corneal surfaces, promote physiological wound healing or extend the residence time of topically applied drugs in the eye, or for use in ophthalmic visco-elastic devices for injection during eye surgeries incorporating hyaluronic acid (HA) in ophthalmic medical device manufacturing brings many benefits.
Extend drug retention and promote tissue healing
HA is naturally present between the eye and the retina lining, providing shape, volume, and structure. With its strong moisturization properties and ability to extend drug retention and promote tissue healing, HA is a natural choice as an ingredient/excipient for ophthalmic device manufacturing and drug formulation.
Animal-free, Q7 cGMP compliant hyaluronic acid
Not only is Hyasis®, Bacillus-derived HA manufactured to Q7 cGMP standards in a completely animal-free, regulatory-compliant process, it has a dissolving time of up to five times faster when compared to competing Streptococcal- or rooster comb-derived HA on the market.
- Provides optimal viscosity profiles for convenient application and increased patient comfort and compliance
- Produced without animal-derived raw materials or organic solvents for low risk of adverse events in patients
- Ultrapure material with particularly low amounts of nucleic acids, proteins, bacterial endotoxins, and microbial contamination for reduced risk of contamination
- Short filtration time allowing streamlined and more efficient manufacturing of final products
- Superior molecular weight retention upon autoclaving without loss of product viscosity
- Increases drug retention time and enhances drug bioavailability
- Moisturizes and lubricates the corneal surface
- Well tolerated, safe and biocompatible.
Download the eye care application sheet to learn more.